GSK5959

Product Name: GSK5959
CAS No.: 901245-65-6
Chemical Name: GSK5959
Synonyms: CS-1636;GSK5959;BRPF1-IN-3;GSK-5959;GSK5959;N-[2,3-Dihydro-1,3-dimethyl-2-oxo-6-(1-piperidinyl)-1H-benzimidazol-5-yl]-2-methoxybenzamide;Benzamide, N-[2,3-dihydro-1,3-dimethyl-2-oxo-6-(1-piperidinyl)-1H-benzimidazol-5-yl]-2-methoxy-;BRPF3,GSK5959,bromodomain,Inhibitor,inhibit,BRD1,BRPF1,Epigenetic Reader Domain,GSK-5959,GSK 5959,BRPF2,epigenetics
CBNumber: CB23040788
Molecular Formula: C22H26N4O3
Formula Weight: 394.47
MOL File: 901245-65-6.mol

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GSK5959 Property

Boiling point:: 527.3±50.0 °C(Predicted)
Density: 1.263±0.06 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMSO : 13 mg/mL (32.96 mM; Need ultrasonic and warming)
form: Powder
pka: 13.06±0.20(Predicted)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 18123
Product name: GSK5959
Purity: ≥98%
Packaging: 1mg
Price: $32
Updated: 2024/03/01

Cayman Chemical

Product number: 18123
Product name: GSK5959
Purity: ≥98%
Packaging: 5mg
Price: $100
Updated: 2024/03/01

Cayman Chemical

Product number: 18123
Product name: GSK5959
Purity: ≥98%
Packaging: 10mg
Price: $184
Updated: 2024/03/01

Cayman Chemical

Product number: 18123
Product name: GSK5959
Purity: ≥98%
Packaging: 25mg
Price: $381
Updated: 2024/03/01

Tocris

Product number: 5385
Product name: GSK5959
Purity: ≥99%(HPLC)
Packaging: 10
Price: $159
Updated: 2021/12/16

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GSK5959 Chemical Properties,Usage,Production

Description

GSK 5959 exhibits >100-fold selectivity for BRPF1 (IC50 = 80 nM) over a panel of 35 other bromodomains, including BRPF2/3 and BET family bromodomains. Inhibits BRPF1 interaction with histone H3.3, which is involved in the epigenetic regulation of gene expression and have been implicated in human cancer.

Uses

GSK5959 is as elective BRPF1 bromodomain inhibitor.

storage

Store at +4°C

GSK5959 Preparation Products And Raw materials

Raw materials

Preparation Products

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GSK5959 Suppliers

China 49 United Kingdom 1 United States 14 Global 64

901245-65-6, GSK5959Related Search:

GSK8612 4-[2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-[(3S)-3-piperidinylmethoxy]-1H-imidazo[4,5-c]pyridin-4-yl]-2-methyl-3-butyn-2-ol 1-(1-(3-methoxyphenyl)-7-propoxyindolizin-3-yl)ethanone GSK8612 GSK6853 2-Cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl-benzoicacid GSK620 GSK591 ROR gamma-t-IN-1 GSK872

GSK5959

BRPF1-IN-3

N-[2,3-Dihydro-1,3-dimethyl-2-oxo-6-(1-piperidinyl)-1H-benzimidazol-5-yl]-2-methoxybenzamide

GSK-5959;GSK5959

CS-1636

Benzamide, N-[2,3-dihydro-1,3-dimethyl-2-oxo-6-(1-piperidinyl)-1H-benzimidazol-5-yl]-2-methoxy-

BRPF3,GSK5959,bromodomain,Inhibitor,inhibit,BRD1,BRPF1,Epigenetic Reader Domain,GSK-5959,GSK 5959,BRPF2,epigenetics

901245-65-6

Inhibitors